Depends on where you live. If you’re in a deep red state where your Senators won’t have to deal with any serious primary challengers or a real general election threat, it may not do any good.

If they won by a slim margin and their state is trending blue/purple, then it might.

It never hurts to do it.

If enough of their constituents express displeasure, they’ll know that they have to change their ways to keep their positions.