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I’ll give a shout out to Fictorum, which is kinda janky but is a physics-heavy wizard simulator with on-the-fly spellshaping and some real wild spellslinging combos. Between the combat levels, there’s a travel/encounter-type rpg thing vaguely similar to FTL as you try to stay ahead of a wave of Bad Thingstm
Have you played Assassin’s Creed: Freedom Cry? It’s not a perfect fit but you do get to hunt down slavers and slave ships.